Active
| Player | # | Pos | HT | WT | Age | Exp | College |
|---|---|---|---|---|---|---|---|
| Mitchell Agude | 50 | LB | 6-4 | 245 | 25 | R | Miami |
| Maurice Alexander | 15 | WR | 5-11 | 174 | 27 | 1 | Florida International |
| Alex Anzalone | 34 | LB | 6-3 | 238 | 29 | 7 | Florida |
| Michael Badgley | 17 | K | 5-10 | 188 | 28 | 6 | Miami |
| Derrick Barnes | 55 | LB | 6-0 | 240 | 24 | 3 | Purdue |
| Mathieu Betts | N/A | LB | N/A | N/A | N/A | 2 | Laval |
| Brian Branch | 32 | DB | 6-0 | 203 | 22 | R | Alabama |
| Jack Campbell | 46 | LB | 6-5 | 243 | 23 | R | Iowa |
| John Cominsky | 79 | DL | 6-5 | 285 | 28 | 5 | Charleston |
| Scott Daly | 47 | LS | 6-1 | 245 | 30 | 3 | Notre Dame |
| Marcus Davenport | N/A | OLB | 6-6 | 265 | 27 | 6 | Texas-San Antonio |
| Carlton Davis | N/A | CB | 6-1 | 206 | 27 | 6 | Auburn |
| Taylor Decker | 68 | T | 6-7 | 318 | 30 | 8 | Ohio State |
| Khalil Dorsey | 30 | CB | 5-8 | 185 | 25 | 3 | Northern Arizona |
| Matt Farniok | 66 | G | 6-5 | 316 | 26 | 3 | Nebraska |
| Daurice Fountain | 84 | WR | 6-2 | 210 | 28 | 4 | Northern Iowa |
| Jack Fox | 3 | P | 6-2 | 218 | 27 | 4 | Rice |
| Jake Funk | 36 | RB | 5-10 | 205 | 26 | 2 | Maryland |
| Connor Galvin | 76 | OL | 6-7 | 300 | 25 | R | Baylor |
| Jahmyr Gibbs | 26 | RB | 5-9 | 200 | 21 | R | Alabama |
| Steven Gilmore | 24 | CB | 6-0 | 174 | 24 | R | Marshall |
| Graham Glasgow | 60 | OL | 6-6 | 315 | 31 | 8 | Michigan |
| Jared Goff | 16 | QB | 6-4 | 217 | 29 | 8 | California |
| Antoine Green | 80 | WR | 6-2 | 199 | 24 | R | North Carolina |
| Hendon Hooker | 12 | QB | 6-3 | 220 | 26 | R | Tennessee |
| Aidan Hutchinson | 97 | DL | 6-7 | 268 | 23 | 2 | Michigan |
| Craig James | 33 | CB | 5-10 | 195 | 27 | 3 | Southern Illinois |
| Jermar Jefferson | 39 | RB | 5-10 | 215 | 23 | 2 | Oregon State |
| Brandon Joseph | 40 | S | 6-0 | 200 | 23 | R | Notre Dame |
| Kerby Joseph | 31 | S | 6-1 | 203 | 23 | 2 | Illinois |
| Tom Kennedy | 85 | WR | 5-10 | 195 | 27 | 3 | Bryant |
| Zonovan Knight | 28 | RB | 5-11 | 209 | 22 | 2 | N.C. State |
| Sam LaPorta | 87 | TE | 6-3 | 245 | 23 | R | Iowa |
| Brodric Martin | 98 | DL | 6-5 | 330 | 24 | R | Western Kentucky |
| Alim McNeill | 54 | DL | 6-2 | 315 | 23 | 3 | N.C. State |
| Ifeatu Melifonwu | 6 | S | 6-3 | 210 | 24 | 3 | Syracuse |
| James Mitchell | 82 | TE | 6-4 | 246 | 24 | 2 | Virginia Tech |
| David Montgomery | 5 | RB | 5-11 | 224 | 26 | 5 | Iowa State |
| Emmanuel Moseley | 4 | CB | 5-11 | 195 | 27 | 6 | Tennessee |
| Netane Muti | N/A | G | 6-3 | 315 | 24 | 4 | Fresno State |
| Michael Niese | 62 | OL | 6-5 | 295 | 26 | 1 | Temple |
| Levi Onwuzurike | 91 | DL | 6-3 | 290 | 26 | 3 | Washington |
| Josh Paschal | 93 | DL | 6-3 | 274 | 24 | 2 | Kentucky |
| Frank Ragnow | 77 | C | 6-5 | 310 | 27 | 6 | Arkansas |
| Kalif Raymond | 11 | WR | 5-8 | 180 | 29 | 7 | Holy Cross |
| DJ Reader | N/A | DL | 6-3 | 335 | 29 | 8 | Clemson |
| Jalen Reeves-Maybin | 42 | LB | 6-1 | 226 | 29 | 7 | Tennessee |
| Amik Robertson | N/A | CB | 5-8 | 187 | 25 | 4 | Louisiana Tech |
| Malcolm Rodriguez | 44 | LB | 5-11 | 234 | 24 | 2 | Oklahoma State |
| Penei Sewell | 58 | T | 6-5 | 335 | 23 | 3 | Oregon |
| Dan Skipper | 70 | T | 6-9 | 330 | 29 | 4 | Arkansas |
| Chris Smith | 90 | DL | 6-1 | 305 | 24 | R | Notre Dame |
| Tre'Quan Smith | N/A | WR | 6-1 | 210 | 28 | 6 | UCF |
| Colby Sorsdal | 75 | OL | 6-6 | 315 | 24 | R | William & Mary |
| Amon-Ra St. Brown | 14 | WR | 6-0 | 202 | 24 | 3 | USC |
| Cameron Sutton | 1 | CB | 5-11 | 180 | 29 | 7 | Tennessee |
| Jameson Williams | 9 | WR | 6-1 | 180 | 22 | 2 | Alabama |
| Shane Zylstra | N/A | TE | 6-4 | 240 | 27 | 2 | Minnesota State |
Exclusive Rights Free Agent
| Player | # | Pos | HT | WT | Age | Exp | College |
|---|---|---|---|---|---|---|---|
| Kayode Awosika | 74 | G | 6-3 | 315 | 25 | 2 | Buffalo |
| James Houston | 41 | LB | 6-1 | 245 | 25 | 2 | Jackson State University |
| Chase Lucas | 27 | CB | 5-11 | 184 | 27 | 2 | Arizona State |
| Craig Reynolds | 13 | RB | 5-11 | 216 | 27 | 2 | Kutztown |
Restricted Free Agent
| Player | # | Pos | HT | WT | Age | Exp | College |
|---|---|---|---|---|---|---|---|
| Jerry Jacobs | 23 | CB | 5-11 | 203 | 26 | 3 | Arkansas |
| Benito Jones | 94 | DL | 6-1 | 335 | 26 | 3 | Mississippi |
| Brock Wright | 89 | TE | 6-5 | 250 | 25 | 3 | Notre Dame |
Unrestricted Free Agent
| Player | # | Pos | HT | WT | Age | Exp | College |
|---|---|---|---|---|---|---|---|
| Tyson Alualu | 92 | DL | 6-3 | 304 | 36 | 14 | California |
| Teddy Bridgewater | 10 | QB | 6-2 | 212 | 31 | 10 | Louisville |
| Anthony Firkser | 86 | TE | 6-2 | 245 | 29 | 6 | Harvard |
| Charles Harris | 53 | DL | 6-3 | 250 | 29 | 7 | Missouri |
| Will Harris | 25 | CB | 6-1 | 206 | 28 | 5 | Boston College |
| Jake McQuaide | 43 | LS | 6-2 | 235 | 36 | 13 | Ohio State |
| Matt Nelson | 67 | T | 6-7 | 315 | 28 | 4 | Iowa |
| Romeo Okwara | 95 | DL | 6-4 | 255 | 28 | 8 | Notre Dame |
| Donovan Peoples-Jones | 19 | WR | 6-2 | 204 | 25 | 4 | Michigan |
| Josh Reynolds | 8 | WR | 6-3 | 194 | 29 | 7 | Texas A&M |
| Nate Sudfeld | N/A | QB | 6-6 | 230 | 30 | 7 | Indiana |
| Halapoulivaati Vaitai | 72 | G | 6-6 | 322 | 30 | 8 | Texas Christian |
| Kindle Vildor | 29 | CB | 5-11 | 189 | 26 | 4 | Georgia Southern |
